Claire Gilliam is a guest character who appears in the episode "Karma Chameleon". She is played by Amanda Brooks.
In the original timeline, Claire was a domestic airline flight attendant that had a one night stand with bartender Joel Bender at the Toledo Express Inn. The next morning, she leaves on a flight to Milwaukee, Wisconsin, and never meets Joel again. Claire later gives birth to a son conceived that night named Wes Gilliam. Wes grows up to become the murderer of two women.
In the altered timeline, Garcia Flynn tells Wyatt Logan that Wes was the killer of his wife, Jessica Logan, after his cooperation with a scheme to capture Benedict Arnold. Later, Rufus Carlin and Wyatt steal the Lifeboat, to travel to March 19, 1983, to try and prevent Claire and Joel from conceiving to prevent the murder of Jessica. In the incident, Joel is accidentally killed. When Rufus and Wyatt return, two of the women Wes murdered in the original timeline are alive, but Jessica is still dead.